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Beyond these effects, IF activates autophagy, a cellular quality-control process that facilitates the clearance of misfolded proteins and damaged organelles, including amyloid-beta plaques implicated in Alzheimers pathology [37, 78]

Rev Assoc Med Bras

doi: 10.1186/s13046-017-0566-5, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 297

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Furthermore, MC1R's role may extend beyond pigmentation to include potential actions on anti-inflammatory signaling and the genomic stability of melanocytes, underlining the receptor's multifaceted potential in skin function and disease prevention

Corneal angiogenic privilege and its failure